Gastrointestinal: Whipple's disease
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چکیده
منابع مشابه
Whipples disease: a review
Whipples disease was described in 1907 and given the name intestinal lipodystrophy until it was found that the agent responsible is a bacterium named Tropheryma whipplei. Its a rare disease which occurs predominantly in males aged 30-60. The small intestinal mucosa is always affected with lesions that are specific to this disease. Replacement of most of cellular elements in the lamina propr...
متن کاملPeripheral neuropathy in Whipples disease: a case report.
Whipples disease is a chronic multisystem inflammatory disease with predominantly gastrointestinal manifestations due to Tropheryma whipplei infection. Typical neurological abnormalities include dementia, eye movement abnormalities, hypothalamic dysfunction and oculomasticatory myorhythmias. The literature on peripheral neuropathy in Whipples disease is sparse and the involvement of peripheral ...
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Background: Eosinophilic gastrointestinal disorders or diseases (EGIDs) may result from an abnormal immune-mediated response to food antigens. Activated eosinophils release various mediators with inflammatory properties which may result in tissue and subsequently organ damage. The cytokine milieu of these patients has revealed increased levels of pro-inflammatory cytokines, inc...
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Lactoferrin, a major whey protein, is a red iron-binding protein present mainly in external secretions such as breast milk and in polymorphonuclear neutrophils. The presence of lactoferrin in body fluids is proportional to the flux of neutrophils and its assessment can provide a reliable biomarker for inflammation. In gastrointestinal diseases increased fecal lactoferrin is a sensitive and spec...
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The hazards of living without a spleen were recognised by the paediatricians in the early 1960's when they focussed attention on the syndrome of fulminant sepsis, often due to pneumococcal infection, occurring in young children within the fIrst two years of splenectomy 1. A child, well at breakfast, might be febrile by lunch, comatose by evening and dead by the following morning. We now recogni...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2007
ISSN: 0815-9319,1440-1746
DOI: 10.1111/j.1440-1746.2006.04816.x